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Complexity Digest 2011.16 - 14
http://comdig.unam.mx/index.php?id_issue=2011.16#34958
2011/08/19

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Editor-in-Chief: Carlos Gershenson
Founding Editor: Gottfried Mayer

Regenerative medicine: Bespoke cells for the human brain, Nature
 









Excerpt: A major goal for biomedical researchers has been to repair damaged
cells and tissues by reinitiating the body's developmental mechanisms. In this
respect, the use of embryonic stem cells â€" and of induced pluripotent stem
cells, which are generated by reprogramming differentiated adult cells â€" has
seemed promising. But these cells come with various problems, including ethical
concerns, and potential tumorigenicity and rejection by the host immune system.
Three papers in this issue describe the direct conversion of neurons from skin
fibroblast cells. There is hope, although no compelling evidence, that neurons
generated in this way might be superior to those generated from induced
pluripotent stem cells, thereby sidestepping the problems of using such cells
Source: Regenerative medicine: Bespoke cells for the human brain[
http://dx.doi.org/10.1038/476158a ], Michael Sendtner, DOI: 10.1038/476158a,
Nature  476, 158â€"159, 2011/08/10

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