[ Your Name ]  would like to inform you about this article on
Complexity Digest 2008.40 - 12
http://comdig.unam.mx/index.php?id_issue=2008.40#31322
3-Oct-2008

[ Your Message ]

PDF files of our annual editions are available at
http://www.comdig.de/AnnualEditions.html

A letter from Gottfried Mayer to our readers and friends is at
http://www.comdig.de/GMLetter.html

Cancer: Entangled Pathways, Nature
 









Excerpts: A medley of molecules, and the interactions between them, mediate
cancer. The latest news is that the enzyme CDK8 orchestrates cross-talk between
two signalling pathways that are frequently deregulated in human cancers.  There
is no simple answer to the question of which cellular proteins or signalling
pathways are responsible for making a cell cancerous. (...) Mutations in the
gene for the retinoblastoma tumour-suppressor protein, which is part of another
signalling pathway, are also frequently associated with cancer. When put
together, the findings of Firestein et al. and Morris et al., presented in this
issue, lead to the identification of a point at which these important pathways
could communicate with each other in colorectal cancer.
Source: Cancer: Entangled Pathways[
http://www.nature.com/nature/journal/v455/n7212/full/455479a.html ], Rene
Bernards, DOI: 10.1038/455479a, Nature 455, 479-480, 08/09/25

You can discuss this article on Articles Forum
http://comdig.unam.mx/topic.php?id_article=31322