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Complexity Digest 2008.39 - 07.01
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26-Sept-2008

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Cancer: Hedgehog's Other Great Trick, Nature
 









Excerpts: The poet Archilochus wrote "The fox has many tricks, and the hedgehog
one great one". Yet a signalling-pathway namesake of hedgehog may have two great
tricks that could be exploited for cancer therapy. Molecular signalling pathways
that control the growth of cancer cells have been heralded as prime targets for
the treatment of a broad spectrum of tumours. Of particular interest is the
hedgehog pathway, which normally is involved in development but whose abnormal
activity is thought to drive the proliferation of cancer cells.
Source: Cancer: Hedgehog's Other Great Trick[
http://www.nature.com/nature/journal/v455/n7211/full/455293a.html ], Tom Curran,
Jessica M. Y. Ng, DOI: 10.1038/455293a, Nature 455, 293-294, 08/09/18

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