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4-Sept-2008

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Systems Biology: Reverse Engineering The Cell, Nature
 









Excerpts: Borrowing ideas that were originally developed to study electronic
circuits, two reports decipher how yeast reacts to changes in its environment by
analysing the organism's responses to oscillating input signals. (...) Using the
microfluidics set-up, they were therefore able to measure the transcriptional
response of galactose-utilizing genes to oscillations of glucose concentration
at different frequencies. They found that the yeast reacts strongly to slow
oscillations in glucose levels, but weakly to fast oscillations.
Source: Systems Biology: Reverse Engineering The Cell[
http://www.nature.com/nature/journal/v454/n7208/full/4541059a.html ], Nicholas
T. Ingolia, Jonathan S. Weissman, DOI: 10.1038/4541059a, Nature 454, 1059-1062,
08/08/28

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