Genomics: New Haplotype Map May Overhaul Gene Hunting

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Complexity Digest 2005.44 - 10
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05/11/03

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Genomics: New Haplotype Map May Overhaul Gene Hunting, Science
 









Excerpts: The map allows gene hunters to get away with less (and thus cheaper)
DNA sequencing while still, it's hoped, homing in on disease genes. The current
HapMap--a finer-resolution version will come out next year--includes more than 1
million SNPs drawn from the DNA of 269 individuals from four different
populations, because haplotype frequencies vary based on evolutionary history.
(...)
(...), as hoped, a select set of SNPs reliably defines the DNA surrounding them,
making it possible to locate relevant genes by comparing haplotype patterns in
different groups.
Source: Genomics: New Haplotype Map May Overhaul Gene Hunting[
http://www.sciencemag.org/cgi/content/full/310/5748/601a ], Jennifer Couzin,
Science: 60, 05/10/28

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