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08-Aug-2005

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A Possible Unifying Principle For Mechanosensation, Nature
 









Excerpts: Of Aristotle's five senses, we know that sight, smell and much of
taste are initiated by ligands (...); however, the mechanical sensations of
touch and hearing remain without a clear understanding of their molecular basis.
Recently, the relevant force-transducing molecules¡Xthe mechanosensitive ion
channels¡Xhave been identified. Such channel proteins purified from bacteria
sense forces from the lipid bilayer in the absence of other proteins. Recent
evidence has shown that lipids are also intimately involved in opening and
closing the mechanosensitive channels of fungal, plant and animal species.
Source: A Possible Unifying Principle For Mechanosensation[
http://www.nature.com/nature/journal/v436/n7051/full/nature03896.html ], Ching
Kung, DOI: 10.1038/nature03896, Nature 436, 647-654, 05/08/04

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